Digidrotahisterol

 Digidrotahisterol formula

Digidrotahisterol - a drug that affects the function of the parathyroid and thyroid glands.

Pharmacological action

Application digidrotahisterol positively affects the metabolism of calcium and phosphorus, increases calcium absorption in the intestine and urinary excretion of phosphorus.

Product form

Digidrotahisterol discharged as an oil solution and drops.

Common analogues digidrotahisterol - Tahistin, A.T.10.

Indications digidrotahisterol

Digidrotahisterol indicated for the treatment of hypocalcemia, resulting in the background or pseudohypoparathyreosis hypoparathyroidism, treatment of renal osteodystrophy, tetany, family hypophosphatemia, which developed because of the vitamin D-sustainable rickets.

Dosing digidrotahisterol

Digidrotahisterol taken orally during or after meal at 0, 5 mg three p / day every day. At steady decrease in the concentration of calcium - at 0, 75 mg three p / day. The maximum daily dose - 1, 5-2, 25 mg.

After 7-10dn. treatment if there is a change in the concentration of phosphorus and calcium, switching to maintenance therapy - 0, 5-1, 5 mg per day digidrotahisterol one to three p / week. On average, 0, 5 mg is 12 drops money.

For the treatment of familial hypophosphatemia take 0, 5-2mg / day. Maintenance Dosage - 0 2-1 5 mg per day.

When tetany give 0, 75-2, 5 mg / day for three days. If you get better, you can take 0, 25-0, 5 mg to  Digidrotahisterol
 Over the next three days. During maintenance therapy take 0, 25 mg / day of a week.

For the treatment of hypoparathyroidism administered 0, 75-2, 5 mg dihydrotachysterol per day. Supportive care - 0. 2-1mg per day.

When renal osteodystrophy give 0, 1-0, 25 mg / day. Supportive care - 0. 2-1mg per day.

Analogs digidrotahisterol used according to their instructions.

Side effects

Application digidrotahisterol can cause allergic reactions, cause nausea.

It may be hypervitaminosis of vitamin D with characteristic symptoms: diarrhea, constipation, thirst, headache, dryness of the mouth, pollakiuria, polyuria, vomiting, nocturia, anorexia, metallic taste in the mouth, hypercalcemia, asthenia, fatigue, hypercalciuria, clouding of urine, increasing pressure , bone pain, photosensitivity of the eye, arrhythmia, itching, drowsiness, flushing, pancreatitis, conjunctivitis, myalgia, gastralgia.

When using digidrotahisterol may arise chronic intoxication with vitamin D, which is expressed hypertension, vascular calcification, lung, soft tissue, kidney failure, cardiovascular, renal, impaired growth in children. For the treatment of intoxication should be abolished preparation comply with bed rest, a diet low in calcium, taking a laxative, drink plenty of fluids.

Contraindications

Application digidrotahisterol contraindicated in patients with high blood levels of calcium.





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