Tsitizin

Cytisine - preparation for correcting violations in alcoholism and drug addiction.

Pharmacological action

The drug has  Plaster Tsitizin
   stimulating effect on the H-cholinergic receptors, which contributes to the reflex stimulation of the respiratory center of the medulla oblongata. Cytisine affects holinoreaktivnye adrenal tissue structure, which leads to an increase in epinephrine release, which in turn triggers the mechanisms to increase blood pressure.

Until recently, the drug successfully used in morphine intoxication, carbon monoxide, barbiturates, and other substances that suppress the central nervous system. Currently, due to the use of alternative barbiturates and morphine antagonists, the use of cytisine limited.

The drug has also been used intravenously or intramuscularly, respiratory arrest, circulatory and respiratory inhibition of infectious patients.

Tsitizin actively influences the sensations change from smoking unpleasant, it helps to reduce nicotine addiction. The drug suppresses the manifestation of abstinence at smoking cessation.

The mechanism of action and its effect cytisine approaching pharmacodynamics of nicotine that allows the use of the active ingredients of the drug to completely giving up smoking without the development of the syndrome.

Contraindications cytisine

The instructions to cytisine highlighted a number of contraindications, which include: Hypersensitivity to the active drug components, myocardial infarction, angina, atherosclerosis, stroke, high blood pressure, exacerbation of gastric ulcers and duodenal ulcers, pregnancy, lactation.

Restrictions apply

In a review of cytisine said that use of the drug is not recommended for schizophrenia, adrenal tumors, coronary artery disease, congestive heart failure, cerebrovascular disease, hyperthyroidism, peptic ulcer, diabetes, liver or kidney failure, aged eighteen and over sixty-five .

Application of cytisine in pregnancy

Use of the drug and analogs cytisine is contraindicated during pregnancy due to increased risk of embryotoxic action.

Method of use and dosage of cytisine

The instructions  The analogue cytisine
 to cytisine stated that the tablet form of the drug is taken orally every two hours to 1, 5 mg for three days of smoking cessation. From the fourth to the twelfth day Tsitizin taken in the same dosage every two and a half hours. From the thirteenth to the fifteenth day after the failure - every three hours. From the sixteenth to the eighteenth - every five hours. In the absence of the desired effect, the drug was stopped. The next attempt to receiving cytisine take 2-3 months after completion of the first course.

In a review of cytisine noted that the possible use of the drug in the form of a patch, which is pasted on the forearm. This form of reception facilitates the penetration of active ingredients into the body through the skin surface cytisine. Before mounting the patch wipe the skin with alcohol or with water. Pasted the patch must be protected from water and other liquids. The dosage of the drug in the patch depends on the size and adjusted individually.

The drug is also available in the form of films, which are attached to the sky or the inner surface of the cheek. The film uses every day from four to eight times, from the first to the fifth day of smoking cessation.





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