Crestor

 Crestor 10 mg

Crestor - lipid-lowering drugs used for the treatment and prevention of atherosclerosis.

Pharmacological action

The active substance of CRESTOR exerts hypolipidemic and hypocholesterolemic action.

In the opinion of Crestor compared to peers has a greater ability to lower cholesterol levels, and is well tolerated. Also, compared with analogues Crestor has minimal liver toxicity.

Crestor is used as a standalone product for the treatment of hyperlipidemia and hypercholesterolemia, or as an adjunct to diet or other holesterinosnizhayuschey therapy.

The therapeutic effect of CRESTOR seen a week after initiation of therapy, the maximum effect - from two weeks to a month.

Crestor under the instruction has an effect regardless of gender, age or race. Also on the guest Crestor is effective in diabetes.

Analogs of CRESTOR manufactured by different companies. The most common of them - Merten produced in Russia and produced in the same dosages and Rosuvastatin, Rozulip, Rozukard and others.

To use analog CRESTOR should consult with your doctor.

Product form

Crestor produced in the form of round biconvex pink coated tablets containing 5 mg, 10 mg (Crestor 10), 20 mg, 40 mg active substance rosuvastatin. Other ingredients - microcrystalline cellulose, lactose monohydrate, crospovidone, calcium phosphate and magnesium stearate. At 7 or 14 tablets per blister.

Indications Crestor

According to the instructions Crestor is used for:

  • Primary hypercholesterolemia by Frederickson Type IIa, heterozygous familial hypercholesterolemia including;
  • Mixed type IIb hypercholesterolemia as an adjunct to diet when diet and non-pharmacological treatments are inadequate;
  • Family homozygous hypercholesterolemia in cases of ineffectiveness of other therapy or as a complement to it;
  • Type IV hypertriglyceridemia as an adjunct to diet.

Crestor also instructions for use to slow the progression of atherosclerosis.

Contraindications

The use of CRESTOR 10 and 20 mg is contraindicated in:

  • Myopathy;
  • Severe renal impairment;
  • Liver disease in the active phase;
  • The lack of reliable methods of contraception;
  • Miotoksicheskih predisposition to develop complications;
  • Lactose intolerance and deficit;
  • Hypersensitivity to the CRESTOR;
  • Concomitantly with cyclosporine.

According to the instructions of 40 mg Crestor is contraindicated in:

  • Liver disease in the active phase;
  • Concomitantly with cyclosporine;
  • Renal insufficiency moderately;
  • Hypothyroidism;
  • Excessive alcohol consumption;
  • Simultaneous reception fibrates;
  • The lack of adequate methods of contraception;
  • Deficiency or lactose intolerance.

Also, Crestor 40 mg is contraindicated in patients of Asian race, and in case of hypersensitivity to the drug.

With careful use of Crestor 10, 20 and 40 mg at:

  • Uncontrolled seizures;
  • Excessive alcohol consumption;
  • Sepsis;
  • History of liver disease;
  • Major surgery or trauma;
  • Renal insufficiency;
  • Hypotension;
  • Along with fibrates;
  • Heavy endocrine, metabolic or electrolyte abnormalities.

Instructions for use Crestor

 Crestor 20 mg
 According to the instructions Crestor can be taken regardless of meals and time of day, without chewing or crushing the pill.

Initial dose - once a day 1 tablet Crestor 10, based on the content of cholesterol and taking into account the risk of side effects and cardiovascular complications.

If necessary, a month dose of CRESTOR may be increased.

If abnormal liver function, as well as those of the Asian race or predisposition to myopathy The recommended starting dose is 5 mg per day.

The dose of 40 mg administered only under severe hypercholesterolemia with little effect on the use of 20 mg.

With simultaneous use of CRESTOR with other medications should be careful.

During pregnancy and lactation the use of CRESTOR is contraindicated, and children up to 18 years - is not recommended due to lack of research. Also, care must be taken for women of reproductive age in the application of the drug and to use reliable methods of contraception because of possible risks to the developing fetus.

side effects

In the opinion of Crestor is well tolerated and is rarely causes side effects. When using CRESTOR may occur:

  • Disorders of the thyroid gland;
  • Dizziness;
  • stomach ache;
  • Pancreatitis;
  • Rash;
  • headache;
  • Myalgia;
  • Rhabdomyolysis with acute renal failure or without;
  • Asthenic syndrome;
  • Itching;
  • Nausea;
  • Myopathy, including myositis;
  • Constipation;
  • Hives;
  • Angioedema;

Normally when using Crestor 10 violations of the urinary, musculoskeletal and central nervous system are not observed.

storage conditions

Crestor available on medical prescription, drug shelf life - 3 years.





Яндекс.Метрика