Ciprofloxacin

Ciprofloxacin - broad spectrum of antimicrobial action.

Pharmacological properties

In testimony to ciprofloxacin noted  Ciprofloxacin vial
 that the drug has a pronounced bactericidal effect. Ciprofloxacin gives DNA replication, as well as slowing down the protein synthesis in the bacterial cell structures. The drug is active against microorganisms which are in a resting phase, and during reproduction. Ciprofloxacin has a depressing effect on gram-negative aerobic bacteria, Gram-positive aerobic bacteria, some intracellular pathogens.

Pharmacokinetics Ciprofloxacin

When taken orally active components of Ciprofloxacin drug is rapidly absorbed from the gastrointestinal tract. The maximum concentration of the drug in fluids and tissues after oral administration is achieved in 60-90 minutes. Ciprofloxacin concentration in selected tissues of the body (bile, lungs, kidneys, liver, gall bladder, seminal fluid, uterus, fallopian tubes, ovaries, prostate tissue, tonsils, endometrium) is significantly higher than in serum. Ciprofloxacin drug and analogs successfully penetrate into the bone tissue, ocular fluid, skin, muscle tissue, peritoneum, lymph.

The half-life of the drug in patients with normal renal function is an average of three to five hours. If the kidney function the half-life is significantly increased. Ciprofloxacin is excreted in urine and feces.

Indications Ciprofloxacin

The instructions to ciprofloxacin said that the drug has been used successfully in the treatment of infectious and inflammatory diseases, which are sensitive to the drug provoked viral organisms. Such diseases include: inflammation of the respiratory tract, lung, kidney and urinary system, digestive system, skin, soft tissue, musculoskeletal system. The drug is also used for the treatment and prevention of infectious diseases in the immunosuppressed.

Contraindications Ciprofloxacin

The drug has a number of contraindications, which include hypersensitivity to its active components and counterparts of Ciprofloxacin. The drug should not be used during pregnancy and lactation. Do not use the drug for children and adolescents under the age of eighteen.

Side effects

The instructions to ciprofloxacin noted that the drug is well tolerated. However, in some cases, possible allergic reactions, as well as the development of swelling of the vocal cords, loss of appetite, disorders of the gastrointestinal tract, headaches, the emergence of anxiety, changes in the blood picture.

Cautions

If necessary, use of a drug for the treatment of infections  Ciprofloxacin tablets
 patients with epilepsy, organic brain disease, vascular disease, due to the increased risk of side effects in the central nervous system, it is advisable to appoint Ciprofloxacin solely for health indicators.

When ciprofloxacin during prolonged diarrhea and other disorders of the gastrointestinal tract, should exclude the diagnosis of pseudomembranous colitis, which demands the immediate cessation of drug treatment.

The instructions to ciprofloxacin noted that the appearance of symptoms of pain in the tendons, as well as signs of tenosynovitis, the course of treatment should be stopped immediately.

Form release Ciprofloxacin

The drug is available in the form of coated tablets for 0, 25; 0, 5, 0, 75 g, or in a solution in vials for infusions of 50 and 100 ml (100 or 200 mg).





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