Bonviva - a remedy for osteoporosis.
The pharmacological action of Bonviva
Bonviva contains highly active nitrogen-containing bisphosphonate that inhibits the destruction of bone tissue, prevents bone destruction provoked by the blockade of the work of the sex glands, tumors, retinoids.
At the same time reviews of Bonviva indicate that the active ingredient of the drug does not affect the natural process of bone mineralization, and for women undergoing menopause, reduces pathologically increased bone renewal rate.
The product is produced in pill, solution for intravenous administration.
Analogs Bonviva - Bondronat, ibandronic acid.
Bonviva Bonviva and analogues are used for the prevention and treatment of osteoporosis that develops in women during menopause.
Bonviva tablets are taken as a whole, not dissolving and without chewing, drinking plenty of water - 180-240ml. standing or sitting. To lay down for an hour after taking the drug can not be. Also, during treatment can not drink mineral water with a high content of calcium.
2 Tablets, 5mg take one p / day on one piece for 60min before 1st meal, other medications or vitamins, liquids.
Bonviva 150mg tablets - 1 take one piece p / month for 60 min before the 1st meal, vitamins or medicines fluid. Take the drug is recommended in the same month. If the planning method was passed, and before the next scheduled reception there more than a week, you can take a pill 150mg Bonviva. If less than a week, you should wait for the next scheduled reception, as 1st take more tablets per week is impossible.
The solution according to the instructions Bonviva administered only intravenously, avoiding contact with the drug under the skin or into the artery. Enter solution once every three months - 3mg for 15-30s, bolus. Women during treatment is recommended to take additional vitamin D, calcium. If the next injection is missed, it is necessary to introduce as quickly as possible. After that Bonviva is administered intravenously every three months, starting from the date of the last administration.
During therapy with Bonviva is necessary to control the content of magnesium, calcium, phosphorus, renal function.
For patients with liver disease, moderate, and mild renal impairment Bonviva dose adjustment is required. Older patients and dose adjustment is not required.
Bonviva Bonviva and analogues can cause diarrhea, arthralgia, dizziness, gastritis, dyspepsia, myalgia, headache, rash, urticaria, angioedema, osteonecrosis of the jaw (rare).
Judging by the reviews, Bonviva tablets may cause: ulcers, esophagitis and esophageal stricture, duodenitis, urticaria, back pain, weakness, nausea, dysphagia, flatulence, vomiting, abdominal pain, cramps and stiffness in the muscles.
A solution for intravenous administration can cause gastroenteritis, constipation, briefly reducing the amount of calcium in the blood, pain in the feet, hands, bones, osteoarthritis, depression, insomnia, thrombosis, fatigue, cystitis, bronchitis, upper respiratory tract infection and urinary tract, hypertension, scleritis , uveitis.
Through reviews of Bonviva it was found that an overdose occur heartburn, ulcers, gastritis, dyspepsia, esophagitis, hypophosphatemia, hypocalcemia. For the treatment of drinking milk or taking antacids. Induce vomiting is not recommended - it increases the risk of esophageal irritation. The patient must thus remain in an upright position.
If overdose occurred after intravenous administration, the treatment is carried out by introducing calcium gluconate, sodium phosphate, potassium or magnesium sulfate. Dialysis two hours after poisoning is considered to be ineffective.
Bonviva on instructions do not take in case of hypersensitivity to ibandronic acid, gikpokaltsiemii.
2 tablets, 5 mg, and the solution for injection is not indicated lactating and pregnant women.
The solution is contraindicated in severe renal disease. Tablets 2, 5 and 150 mg in this disease is prescribed with caution.
Children up to 18L Bonviva in osteoporosis is not appointed, as such studies have been conducted.
Tablets Bonviva coated incompatible with products containing calcium, iron, aluminum, magnesium and other polyvalent cations. These products, milk, solid food taken no earlier than 60 min after administration of Bonviva Bonviva and unique inside.
With care prescribe a drug at the same time anti-inflammatory nesteroidami - they irritate the digestive tract.