Azithromycin

 Azithromycin

Azithromycin - antibacterial agent is a broad spectrum of action.

Release form and composition

Azithromycin belongs to the macrolide antibiotics. The active ingredient of the drug has the same name. He is a representative of azalide.

Available in the following dosage forms:

  • Capsules containing 250 mg of azithromycin;
  • Tablets, film-coated, 125 mg, 250 mg and 500 mg;

Excipients:

  • Milk sugar (lactose);
  • MCC;
  • Low molecular weight PVP Medical (povidone);
  • Magnesium stearate;
  • Colloidal silicon dioxide (Aerosil).

Indications

Azithromycin is active against some Gram-positive cocci, Streptococcus group and CF G, Gram negative bacteria, anaerobic microorganisms. Antibiotic sensitivity of chlamydia, mycoplasma, ureaplasma, Treponema spirochete Borrelia.

The drug has no effect on the Gram-positive bacteria resistant to erythromycin.

Azithromycin is expedient at the diseases, which are caused by susceptible to the microorganism. These include infections:

  • Upper respiratory tract - sore throat, sinusitis, tonsillitis, otitis;
  • Lower parts of the chest - pneumonia, bronchitis;
  • Soft tissue and skin - impetigo, erysipelas, dermatitis;
  • Urinary tract - urethritis, cervicitis.

The purpose of this antibacterial agent is also justified in the early stages of Lyme disease.

Contraindications

Azithromycin is contraindicated in persons with hypersensitivity to macrolides. With care prescribe a drug to patients with impaired liver and kidney function.

Dosage and Administration

According to the instructions of azithromycin treatment before the need to check the sensitivity to the hair that caused the disease.

The tablets or capsules are taken orally once a day, one hour before meals or two hours after.

For infections of the respiratory tract, skin and soft tissues of adult appoint 0, 5 g on the first day and 0, 25 g of the following days (2 to 5 days). Also available dosage regimen for 0, 5 g for 3 days.

For the treatment of Lyme disease (borreliosis) in the initial stage of Azithromycin appoint 1 g in the first day, followed by 0, 5 g

The dosage for children is determined by taking into account body weight. If the child's weight over 10 kg, the administered on the first day 10 mg / kg body weight, and then 5 mg / kg, or 3 days at 10 mg / kg.

The missed dose should be taken as soon as possible, and the next - with a break of 24 hours.

Antibiotic resistant to acid medium and is well absorbed from the gastrointestinal tract. Easily penetrates into the skin, soft tissue, respiratory tract and urogenital system tissue.

High concentration of active substance at the site of inflammation provides strong bactericidal effect that is stored 5-7 days after the last dose received. This explains the short duration of treatment (3 and 5 days).

If you plan to co-administration of antacids, then, according to the instructions to azithromycin, the interval between doses of drugs should be at least 2 hours.

side effects

Side effects of azithromycin include:

  • Vomiting;
  • Nausea;
  • Flatulence;
  • A temporary increase in liver enzymes.

In rare cases, there may be a skin rash.

Cautions

Do not use antibiotics during pregnancy, except in cases where the expected benefit to the mother outweighs the potential risk to the child.

At the time of treatment should stop breastfeeding.

Analogs

The active ingredient azithromycin include the following drugs:

  • Azimitsin;
  • Zitrotsin;
  • Sumamed;
  • Hemomitsin;
  • Ekomed and others.

Azithromycin analogues mechanism of action are:

  • Arvitsin;
  • Clarithromycin;
  • Lekoklar;
  • Macropen;
  • Oleandomycin;
  • Rovamycinum
  • Spiramycin Vero;
  • Fromilid;
  • Erythromycin and others.

Terms and conditions of storage

Store in a dry, dark place at a temperature no higher than 25 ° C. Keep away from children. Shelf life - 3 years.





Яндекс.Метрика