Avodart is a drug for the treatment of benign prostatic hyperplasia.
Release form and composition
Avodart is produced in the form of soft yellow oblong capsules labeled «GX CE2», which contained 0, 5 mg dutasteride and auxiliary components: mono-diglycerides of caprylic acid and BHT. The blister packs of 10 capsules.
Dutasteride, Avodart active substance, able to inhibit the activity of enzymes involved in the metabolism of testosterone. The maximum effect as a result of his actions reached after one to two weeks after initiation of medication.
The drug reduces the size of the prostate and improve urinary and reduce the risk of urinary retention in the acute form. According to the instructions, the medication should be administered for the treatment and prevention of benign prostatic hyperplasia.
Avodart is contraindicated in:
- Women and children;
- With high sensitivity to the drug and other drugs related to 5α-reductase inhibitors.
Because dutasteride is extensively metabolized in the liver, caution is required when using Avodart in patients with impaired hepatic function.
Dosage and Administration
Avodart can be administered in combination with tamsulosin, either as monotherapy. Take the drug regardless of the meal. Despite the fact that the positive effect of treatment can occur quite quickly its reception should be continued for at least 6 months.
Adult male, according to instructions Avodart, the recommended dose is 0, 5 mg (1 capsule) per day. To avoid possible irritation of the mucous membranes of the mouth and pharynx capsule is swallowed whole without chewing or opening. The dosage of a medicament for the elderly men and patients with impaired renal function is similar to the dosage for adult males, and does not require correction.
According to clinical studies, use of Avodart as a means to monotherapy can have a number of negative effects, manifested as:
- Decreased libido,
- Abnormal ejaculation,
- Gynecomastia (enlargement and breast pain).
In combination therapy with tamsulosin and Avodart, besides the possibility of such side effects as monotherapy dizziness.
Observations in clinical practice allows to allocate such reactions to the drug, such as itching, rash, urticaria, angioedema, limited swelling.
Women and children should avoid contact with damaged capsules Avodart as the active ingredient is able to absorb the drug through the skin. After contact with dutasteride relevant area of skin should be washed with soap and water.
On the mechanism of action of drugs are analogs of Avodart: Penester, Alfinal, Urofin, Finasta, Sonirid Duo, Finasteride-OBL, Zerlon, Proscar, Finpros, Finasteride, Prosterid.
Terms and conditions of storage
According to the instructions for Avodart, the shelf life of the capsules - 4 years. Store this medication should be at a temperature no higher than 30 ° C in places not accessible to children.