Ampicillin

 Ampicillin

Ampicillin - an antibiotic which suppresses the synthesis of the cell wall of microorganisms, the activity of which appears on many gram-negative and gram-positive bacteria.

Release form and composition

Ampicillin is produced in the form of tablets, capsules and powder for suspension or solution for intravenous and intramuscular administration.

Tablets and capsules of 250 mg of the drug, cellular packaging in 10 or 20 pieces. The powder is sold in banks orange glass on 60, he has a specific smell, white with a yellowish tinge, has a sweet taste.

The active ingredient in all the dosage forms means is ampicillin. The powder also comprises vanillin, sugar and other excipients.

Indications

Use of Ampicillin expedient at the diseases that were caused by mixed infections. Prescribers in the following pathologies:

  • Pneumonia;
  • Pneumonia;
  • Lung abscess;
  • Sore throat;
  • Peritonitis;
  • Cholecystitis;
  • Sepsis;
  • Gonorrhea;
  • Intestinal infections;
  • Postoperative infection of soft tissue;
  • Urinary tract infections caused by Escherichia coli, enterococci, Proteus;
  • Other infections caused by microorganisms sensitive to ampicillin.

Contraindications

According to the instructions, Ampicillin is not appointed in case of hypersensitivity to the active substance, infectious mononucleosis, and hepatic dysfunction.

Dosage and Administration

According to the instructions, it is desirable to prescribe Ampicillin after determining the sensitivity of microorganisms.

The product inside is assigned regardless of the meal.

When administered to adult single dose of 250-500 mg, the multiplicity of reception - 4 times / day. Children weighing up to 20 kg - 12, 5-25 mg / kg every 6 hours.

For intramuscular, intravenous administration of a single dose for adults is 250-500 mg every 4-6 hours. For children, a single dose of 25-50 mg / kg.

The maximum daily dose for adults at intake - 4 g, intramuscular, intravenous injection - 14

The duration of treatment depends on the effectiveness of therapy and disease severity.

side effects

According to the instructions, Ampicillin may cause the following adverse reactions of the body: hives, skin rash, anaphylactic shock, angioedema, conjunctivitis, rhinitis, fever, exfoliative dermatitis, arthralgia, disease, goiter, gastritis, abdominal pain, diarrhea, nausea, vomiting, tremor , headaches, seizures.

Cautions

During the period of Ampicillin requires regular monitoring of peripheral blood, liver and kidney function.

When using high doses of the drug in patients with renal failure can be observed toxic effects on the central nervous system.

Application Ampicillin patients with sepsis, in some cases can lead to bacteriolysis reaction.

Analogs

Ampicillin trihydrate is the most common analogue drug.

Terms and conditions of storage

Keep Ampicillin should be at a temperature not exceeding 25 ° C, in a dry place, away from children.

Shelf life - 2 years.





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