Amigrenin

 Amigrenin
 Amigrenin - remedy for migraine.

Release form and composition

The drug is produced in the form of tablets, film-coated, white in the contour of cellular packages.

The active agent in the composition Amigrenin - sumatriptan, which acts on smooth muscles of the blood vessels of the brain, promotes vasoconstriction carotid activity and suppression of the trigeminal nerve.

Auxiliaries in a preparation are the following components:

  • Microcrystalline cellulose;
  • Potato starch;
  • Lactose;
  • Magnesium stearate;
  • Carboxymethylstarch sodium.

Indications

According to the instructions, Amigrenin prescribed to eliminate the pain caused by migraine with aura and without it.

Contraindications

According to the instructions, you can not appoint Amigrenin:

  • Angina;
  • Heart attack;
  • Uncontrolled hypertension;
  • Ischemia;
  • Stroke;
  • Occlusive peripheral arterial disease;
  • TIAs brain;
  • Kidney and liver failure.

Contraindications to the use Amigrenin are as pregnancy, lactation, age under 18 and over 65 years.

Dosage and Administration

According to the instructions, Amigrenin taken orally, drinking water, regardless of meals.

When an attack is recommended to take 1 tablet (50 mg), in some cases, allowed to take 100 mg.

Permissible daily dose - 300 mg.

If after the application of a single dose (50 mg) attack has not been eliminated, take the second right is not recommended. Take again 50 mg can be used only if the first receiving Amigrenin came relief, but after a while the pain was renewed. The interval between doses tablets should be at least 2 hours.

Amigrenin usually takes effect within half an hour after ingestion.

Side effects

Application Amigrenin in some cases may cause the following side effects:

  • Reduced or elevated pressure;
  • Tachycardia;
  • Bradycardia;
  • Nausea;
  • Vomiting;
  • Weakness;
  • Dizziness;
  • Severe cardiac arrhythmias;
  • Seizures;
  • Epigastric discomfort;
  • Ischemic colitis;
  • Dysphagia;
  • Increase in liver enzymes;
  • Raynaud's syndrome;
  • Fatigue and drowsiness;
  • Partial loss of vision;
  • Diplopia and nystagmus (rare);
  • Allergic reactions (itching, rash, anaphylactic reaction, the nature, myalgia).

Cautions

Do not use the drug as a prophylactic measure.

Be wary appointed Amigrenin controlled epilepsy and hypertension. You can not combine the product with ergotamine and MAO inhibitors (not just once, but over 2 weeks after cessation of administration).

Since there is a possibility of coronary artery spasm, the first 2-3 of the drug is recommended under medical supervision.

You should avoid driving vehicles and using machinery during use Amigrenin, as the drug can cause drowsiness.

Means prescription.

Analogs

Analogues are drugs Amigrenin sumamigren and Antimigren, based the same active ingredient. According to have a therapeutic effect means an analogue acts Zomig.

Terms and conditions of storage

Amigrenin should be stored in dry and protected from sunlight place.

Shelf life is 2 years.





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