Adrenocorticotropic hormone (corticotropin or) refers to a group of hormones. The main component of the drug is prepared from anterior pituitary in cattle or pigs.
Corticotrophin hormone in humans
Adrenocorticotropic hormone present in the body in varying amounts, depending on environmental factors, health status, as well as the emotional state. For example, 6-7 o'clock concentration of the hormone peaks, but to 10:00 PM is reduced to a minimum. If one replaces the residence in a different time zone, the concentration of the hormone ACTH back to normal in a new place only 10 days. Stressful situations or nervous stress may trigger an increase in blood cortisol. Female body suffers from vibrations ACTH before menstruation, during pregnancy, and during intense exercise.
Medicinal properties of ACTH
ACTH is produced is characterized by several effects on the human body. Firstly, the hormone ACTH stimulates the production process in the body steroids (cortisol, estrogen, androgens). Cortisol - the hormone that is found in the adrenal glands, but sometimes - in small quantities, is not enough to enter the bloodstream. With ACTH fails to strengthen its production. Adrenocorticotropic hormone - one of those who are responsible for the process of splitting fat and, therefore, involved in the regulation of body weight.
In the development of muscle tissue corticotropin also plays a big role. It helps them to absorb and be filled with glucose and useful amino acids, which is especially important for athletes. The saturation of the blood hormone ACTH increases the natural pigmentation of the skin.
Indications for admission adrenocorticotropic hormone
The drug is recommended ACTH on frequent appearance of fatigue, chronic sleep deprivation, fatigue as a result of the easiest exercise. Adrenocorticotropic hormone is administered after diagnosis of adrenal insufficiency.
Corticotropin recommended to include in the overall treatment of rheumatism, arthritis, gout, asthma. Quite often it is used to treat skin diseases such as dermatitis, eczema, neurodermatitis. Preparation ACTH also proved effective in the symptomatic treatment of various types of allergy.
Using corticotropin can enhance the therapeutic effect exerted by antibiotics during treatment of tuberculosis.
Rules of admission of adrenocorticotropic hormone
In pharmacies, the drug is sold in powder form of light color. From it, a solution in the proportions necessary for the treatment of a disease. The solution is administered intramuscularly ACTH, not more than four times a day at regular intervals. The general course of therapy with the hormone ACTH should not exceed four weeks. After two or three weeks of treatment can be repeated. An exception is the treatment with adrenocorticotropic hormone diseases such as leukemia, chronic polyarthritis, in which treatment can last for up to eight weeks. Do not exceed the daily dose, which is 30 units of ACTH.
Side effects while taking the drug ACTH
During treatment with adrenocorticotropic hormone may appear swelling, heart palpitations. In some cases, there is an increase in blood pressure, disturbed menstrual cycle in women. Rarely observed growth retardation in children when taking hormone ACTH.
To minimize the occurrence of any side effects and uncomfortable conditions when taking adrenocorticotropic hormone, it is recommended to eat more fresh fruits and vegetables as well as foods high in protein.
Contraindications to receive adrenocorticotropic hormone
The drug is not prescribed to pregnant women, people diagnosed with atherosclerosis, hypertension, heart failure, psychosis, ulcers, diabetes, severe. Very careful preparation are allowed to use for older people.