Acyclovir belongs to the group of drugs possessing antiviral activity.
It refers to a group of antiviral drugs. Suffice it effectively on the herpes simplex virus (skin and mucous membranes) and herpes zoster (a viral infection of the CNS and PNS striking with bubbly rash along the nerves).
Acyclovir helps stop virus replication.
Acyclovir absorption occurs partly by about 20%. Acyclovir half-life of the organism is three hours. Excreted from the body by the kidneys.
The use of acyclovir in herpes helps stop the emergence of a new disease, reduces the spread of her skin and the possibility of complications, accelerates the formation of the crust. When herpes zoster acyclovir reduces pain.
According to the instructions, acyclovir is administered intravenously at a herpes simplex immune-compromised, with severe genital infections, which are caused by herpes simplex infections, which are caused by the herpes zoster virus. Acyclovir is also used to prevent infection, which is caused by the herpes simplex virus in violation of the immune system (chemotherapy, organ transplantation).
According to the instructions, Acyclovir has immunostimulatory effects, that is, strengthening the immune system and activates the body's defenses.
Instructions for use and dose of Acyclovir
According to the instructions, Acyclovir is prescribed orally, intravenously and as a topical (cream and ointment acyclovir).
Acyclovir tablets used in infections that are caused by the herpes simplex virus, as well as for the prevention of this disease in patients with impaired immune systems. Acyclovir tablets used and patients with herpes zoster. Children older than 2 years and adults with herpes simplex appoint 1 tablet Acyclovir 5 times a day, with shingles - 4 tablets 5 times a day. The prevention of infection should take 1 tablet Acyclovir 4 times per day.
Children under two years of half of the prescribed dosage, which is provided for adults. Appoint Acyclovir newborn is not recommended. The course of treatment with acyclovir average of 5 days, with shingles recommended the drug for another 3 days after recovery.
Intravenous acyclovir is prescribed for adults and children over 12 years at a dose of 5 mg per kg of body weight three times a day every 8 hours. When shingles with impaired immune systems Acyclovir dose for intravenous administration of 10 mg per kg every 8 hours. Children from three months to 12 years acyclovir intravenously administered at a dose of 5 mg / kg.
For intravenous use Acyclovir divorce. Acyclovir ampule (250 ml) was diluted in 10 ml of sodium chloride, 0, 9% or solvent.
According to the instructions, Acyclovir may be administered by injection is very slowly (within an hour), or apply a dropper, to the resulting solution should be diluted in 50 ml of solvent.
In case of violation of renal excretory function and the elderly dose should be reduced.
Eye ointment Acyclovir is used in inflammation of the cornea, which is caused by the herpes simplex virus (herpes keratitis). Acyclovir ointment is necessary to lay in the conjunctival sac five times a day at intervals of 4 hours. The duration of treatment with ointment Acyclovir is about 7-10 days. Acyclovir Ointment should be used even 3 days after the disappearance of symptoms.
Acyclovir cream is used on the skin and mucous membranes that are affected by herpes simplex virus (on the lips, genitals). According to the instructions, acyclovir as a cream is applied to the surface 5 times per day treatment is from 5 to 10 days depending on the severity of the disease.
According to the instructions to acyclovir, the drug was well tolerated.
If ingestion of tablets Acyclovir may develop side effects such as headache, diarrhea, nausea, vomiting, allergies, fatigue.
When administered intravenously, and when taken in pill form in the assays can be observed the high content of urea and creatinine and bilirubin in serum. It can be observed increase in liver enzymes.
When administered subcutaneously Acyclovir may develop a local reaction.
Contraindication to Acyclovir is intolerance of components.
Data on acyclovir during pregnancy and breastfeeding is not fully understood.