Acetylcysteine

 Acetylcysteine ​​- powder for solution
 Acetylcysteine ​​- a synthetic drug, vasoconstrictor and mucolytic effect, used to treat ENT diseases.

Pharmacological action

The active substance acetylcysteine ​​helps liquefy mucus and increase in its volume. The drug, exerting vasoconstrictor and mucolytic effect, promotes and facilitates expectoration sputum. In addition, according to the instructions acetylcysteine ​​has an antioxidant effect.

Product form

Acetylcysteine ​​is produced in the form of tablets, solution for inhalation and a solution for injection. The drug is available under various brand names - acetylcysteine, NAC, Rinofluimutsil, Atsestin Weeks asset, the AD FS Mukoneks, Fluimucil. Analogs Acetylcysteine ​​is available in different dosage forms:

  • Effervescent tablets - Atsestin, ACC, ACC Long, Fluimucil, H-AC-Ratiopharm;
  • Nasal Spray - Rinofluimutsil;
  • Tablets - Atsestin;
  • Solution for injection - ACC injective, Fluimucil;
  • Granules for syrup - Mukoneks, ACC;
  • Granules and powder for oral solution - NAC, Acetylcysteine-Sedico, Fluimucil, H-AC-Ratiopharm.

Indications for use of acetylcysteine

 Acetylcysteine ​​- a drug used to treat ENT diseases
 Acetylcysteine ​​on the instructions prescribed for respiratory diseases and conditions, which are accompanied by the formation of muco-purulent and viscous sputum:

  • Acute and chronic bronchitis;
  • Trachea, resulting bacterial or viral infection;
  • Bronchiectasis;
  • Bronchial asthma;
  • Sinusitis - to facilitate the discharge of secretions;
  • Cystic fibrosis, in combination therapy;
  • Pneumonia;
  • Atelectasis caused by occlusion of the bronchi of the mucous plug.

Acetylcysteine ​​is also indicated for post-traumatic and postoperative conditions for the removal of viscous secretions from the respiratory tract.

Contraindications

According to the instructions acetylcysteine ​​contraindicated apply at:

  • Gastric ulcer and duodenal ulcer in the acute phase;
  • Pulmonary hemorrhage;
  • Coughing up blood;
  • Hypersensitivity to the active substance acetylcysteine.

The use of acetylcysteine ​​during pregnancy and breastfeeding is possible only under strict conditions.

In bronchial asthma, and diseases of the adrenal glands, kidneys and liver acetylcysteine ​​should be used with caution. The drug under the strict supervision of a physician on the testimony can be used in neonates.

Dosing acetylcysteine

Adults and children over 14 years are usually given 600 mg acetylcysteine, which can be taken as a one-off, and dividing by three steps. For children 6-14 years, the daily dose should not exceed 400 mg. Children 2-5 years should receive acetylcysteine ​​as effervescent tablets of 200-300 mg per day, divided into several times.

For colds acetylcysteine ​​take 5-7 days. In severe cases the duration of the drug is determined individually by your doctor. Treatment of bronchitis and cystic fibrosis requires a longer use of the drug.

Acetylcysteine ​​as a solution for injection administered intramuscularly once a day for adults - 300 mg, for children - 150 mg. Acetylcysteine ​​used for inhalation of 2-5 ml of 20% solution for 15-20 minutes.

If necessary, use analog acetylcysteine ​​should consult a doctor.

Do not be taken simultaneously with acetylcysteine ​​antitussives due to suppression of the cough reflex, which can lead to stagnation of phlegm. Between taking antibiotics and acetylcysteine ​​should observe an interval of at least 1-2 hours.

Side effects of acetylcysteine

Using drugs and analogs acetylcysteine ​​side effects are rare. Most often, the drug according to instructions is:

  • Heartburn, nausea, vomiting, diarrhea, sensation of fullness;
  • Nasal bleeding and tinnitus;
  • Skin rash, itching, hives, bronchospasm.

When using acetylcysteine ​​inhalation possible local irritation of the respiratory tract, cough reflex and, much more rarely, stomatitis or rhinitis. In applying the drug to be injected at a shallow intramuscular injection may appear slight burning sensation.





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