Acetaminophen - a common analgesic commonly used for the relief of pain of various origins.
Acetaminophen has analgesic, antipyretic and anti-inflammatory effect was less marked. The drug begins to have effect within 10-15 minutes after ingestion. When used in doses exceeding therapeutic, acetaminophen can cause disorders of the liver, kidneys and circulatory system.
Acetaminophen is produced in the form of tablets containing 500 mg of active compound paracetamol, if 30 to 12 tablets per pack.
Indications of the drug acetaminophen
Acetaminophen according to the instructions indicated for use in low and moderately expressed pain syndrome:
- Pain in trauma;
- Dental and headache;
Acetaminophen is also used in infectious and inflammatory diseases accompanied by a feverish state.
According to the instructions to use Acetaminophen is contraindicated in case of:
- Severe renal failure;
- Severe anemia;
- Hypersensitivity to the components of acetaminophen.
The drug is not recommended for use under the age of 12 years, and during pregnancy Acetaminophen should be used with caution, especially in the third trimester.
Also use caution when the drug:
- Viral hepatitis;
- Kidney and liver failure;
- Coronary heart disease;
- Cerebrovascular diseases;
- Dyslipidemia or hyperlipidemia;
- Chronic heart failure;
- Peripheral arterial disease;
- Alcoholic liver disease and alcoholism;
- Severe somatic diseases.
Acetaminophen is recommended to take a few hours after eating. A single dose of 500 mg, in cases severe pain syndrome can take the maximum single dose of 1 g acetaminophen instructions for taking four times per day. Do not exceed the recommended maximum daily dose of 4 g, and continue taking the drug longer than a week to avoid the appearance of symptoms of overdose, which can be expressed as nausea, anorexia, vomiting and abnormal liver function.
If you need to use acetaminophen during pregnancy, human liver and kidneys, Gilbert's syndrome, as well as in the elderly, it is recommended to reduce the daily dose and reduce the duration of the drug and drink plenty of fluids tablets.
Care should be taken while taking Acetaminophen with other anti-inflammatory and antipyretic drugs, because they may also contain acetaminophen. Do not take acetaminophen at the same time with oral corticosteroids, anticoagulants and aspirin.
Side effects of Acetaminophen
Acetaminophen can cause a variety of adverse effects:
- Violations of the gastrointestinal tract, manifested in the form of nausea or vomiting;
- Allergic reactions manifesting as itching, angioedema, rash, and urticaria;
- Interstitial nephritis and necrosis of the capillary;
- Thrombocytopenia, methemoglobinemia, anemia, pancytopenia, agranulocytosis.
During treatment with acetaminophen should abandon the use of alcohol because of the increasing risk of destruction of liver tissue.
Acetaminophen - OTC medication with a recommended shelf life of 3 years.