Ibufen - a non-steroidal anti-inflammatory drug.
Pharmacological action Ibufena
Ibufen has well expressed analgesic, antipyretic and anti-inflammatory properties. The main active ingredient - Ibuprofen belongs to a group of non-narcotic drugs. The mechanism of action Ibufena directly associated with inhibition of prostaglandin synthesis, which leads to an effective reduction in the intensity of inflammation and generation of the nerve structures of pain impulses as well as normalization of body temperature. The drug has a significant influence on the synthesis of prostaglandins, it happens due to the inhibition of the cyclooxygenase enzyme, which plays an important role in the formation of prostaglandins and arachidonic acid metabolism.
Antipyretic effect begins to develop at the end of half an hour after oral reception Ibufena, and its maximum is reached in 3 hours. It was after the oral drug is well absorbed in the gastrointestinal tract.
The preparation is characterized by a high degree of association with plasma proteins.
Ibufen available as a suspension for oral administration in glass bottles of 100 ml complete with the metering device.
Instruction Ibufenu states that the drug is intended for the relief of pain in children, including the eruption of primary teeth.
Used Ibufen in the treatment of influenza and SARS. It may be assigned and post-vaccination reactions.
Contraindications to the use Ibufena are:
- individual hypersensitivity to any component of the formulation;
- "Aspirin triad" in history;
- peptic ulcer of the stomach and duodenum;
- a bleeding disorder;
- bleeding tendency;
- severe heart failure;
- hemorrhagic diathesis;
- pregnancy (especially third trimester);
- severely impaired renal function / liver.
You can not prescribe medication Ibufenom patients who undergo therapy non-narcotic analgesics.
Instructions Ibufena: methods of use
According to the instructions, Ibufen intended solely for oral administration. Recommended Shake vial before use until until a homogeneous mass. To reduce the risk of any side effects, you should take the drug only after a meal. The doses of the drug, as well as the duration of treatment, has the right to determine the only doctor.
When hyperthermia and pain syndrome in children usually assigned 20-30 mg per 1 kg of body weight per day of the drug. Share the daily dose should be approximately 3-4 reception. In 5 ml of the preparation contains 100 mg of ibuprofen.
If within 3 days of treatment and improvement is not achieved or there are various negative consequences, we should again see a doctor, so he adjusted the treatment regimen and spent re-inspection.
The most common drug is tolerated quite well, only in rare cases can develop a variety of side effects.
For example, the gastrointestinal tract can react to receiving Ibufena nausea, vomiting, epigastric pain, flatulence, dyspepsia, gastritis, a violation of the chair. On the part of the cardiovascular system are possible: cardiac dysfunction, leukopenia, increased blood pressure, thrombocytopenia.
In addition, allergic reactions may occur, cause dizziness, headache, tinnitus, fatigue, etc.
Conditions and terms
It is recommended to keep the medication in a dark and dry place at 15-25
C. Shelf life Unopened vials 3 years, and after opening Ibufen can be stored for six months only.