Mezaton

 Mezaton
 Mezaton - vasoconstrictor.

Pharmacological action

Effect of the drug Mezaton is directed to stimulation of alpha-adrenergic receptors, which in turn causes vasoconstriction, increased heart rate, bronchodilation, increased blood pressure, inhibition of peristalsis.

Drops Mezaton used in ophthalmic practice, can reduce intraocular pressure, and dilated pupils.

The active ingredient is phenylephrine hydrochloride mezaton, the therapeutic effect of which can be compared with a similar effect of adrenaline. Advantage phenylephrine compared with epinephrine, it is longer acting, and the possibility of using not only parenterally but also orally.

Indications mezaton

Mezaton instructions recommended for hypotension, collapse, intoxications, preparation for operations, as well as during their implementation.

Nasal drops Mezaton prescribed to relieve nasal breathing with the flu, colds, hay fever and other allergic reactions, which are accompanied by acute sinusitis or rhinitis.

Eyedrops Mezaton used to mydriasis at various ophthalmic procedures, including diagnostic and for the symptomatic treatment and prevention iritis and iridocyclitis.

Contraindications

Mezaton instruction prohibits the use in hypertension, atherosclerosis, addiction to vasospasm, ventricular fibrillation, pheochromocytoma, hepatitis and acute pancreatitis.

Intranasal use of phenylephrine is contraindicated in diseases of the cardiovascular system, diabetes, thyrotoxicosis, hypertensive crisis and simultaneous reception of MAO inhibitors.

Eye drops Mezaton not prescribed for narrow-angle and angle-closure glaucoma, slezoproduktsii violation, violation of the integrity of the eyeball.

Apply Mezaton instruction is not recommended in case of hypersensitivity to phenylephrine during pregnancy and lactation.

Instructions for use mezaton

Mezaton is available in tablet form (0, 01 g), 1% solution in ampoules, nasal and eye drops.

During collapse Mezaton instruction recommends slow intravenous injection: 0, 1-0, 5 ml solution diluted in 20 ml of dextrose (5%) or a solution of NaCl (0, 9%). If necessary, drug administration may be carried out repeatedly. For intravenous drip solution diluted in 1ml 250-500 ml dextrose (5%). Application is also possible in mezatonom subcutaneous or intramuscular injections - on 0, 3-1 ml of solution administered 2-3 times per day.

Mezaton topically it may be used in the form of 0, 25-0, 5% solution for irrigation or lubrication of the mucous membranes.

Oral mezaton assumes receive 2-3 times a day for 0, 01-0, 025 grams of the drug in pill form.

Nasal drops Mezaton buried in each nostril every 6 hours: In children younger than 1 year - 1 drop, children 1-6 years - 1-2 drops, children over 6 years and adults - 3-4 drops. The duration of treatment should not exceed three days.

 Mezaton eye drops
 Eye drops Mezaton during ophthalmological procedures administered once in the conjunctival sac of 1 drop, if necessary, after 1 hour instillation may be repeated.

When uveitis (inflammation of the choroid), the drug is used to suspend the inflammatory process - 2-3 times a day 1 drop.

side effects

Mezaton, the application should only be prescribed by a doctor can cause undesirable effects such as:

  • dizziness, weakness, insomnia, anxiety, restlessness, tremors, convulsions, headache;
  • high blood pressure, bradycardia, arrhythmia, kardialgiya;
  • digestive disorders;
  • pale skin, allergic reactions.

Parenteral administration mezaton can cause ischemia of the skin at the injection site in contact with the drug in the tissue or subcutaneous injection may cause scab and necrosis.

Intranasal use of phenylephrine may lead to tingling, burning or tingling in the nose.

Eye drops Mezaton can cause adverse reactions in the form of burning, blurred vision, discomfort, irritation, tearing, increased intraocular pressure, reactive miosis (pupillary constriction) on the second day of treatment.

Additional Information

Storage preparation Mezaton should be done at room temperature in a dark place. Shelf life of solution for injection - 3 years drops - 2 years.





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