Concor

 Concor 10 mg
 Concor - a drug that affects the peripheral nervous system.

Pharmacological action

Concor - a beta adrenablokator no membrane stabilizing action, not having symptomatic activity.

The active ingredient of the drug - bisoprolol hemifumarate. The substance reduces the activity sympathoadrenal blocks cardiac β 1 adrenergic receptors.

A single domestic use of the drug by patients who have no signs of congestive heart failure, reduces heart rate, cardiac stroke volume, ejection fraction, myocardial oxygen demand.

Prolonged use of Concor reduces elevated total peripheral vascular resistance.

Maximum efficiency of the drug reaches across 3-4ch after internal use. Even when using a tablet Concor p / day its effect persists for days.

Judging by the reviews of Concor, the maximum pressure drop observed in 2ned. after initiation of therapy.

The drug has no effect on reducing the strength of heart contractions.

Product form

Release tablets Concor. Another brand name of the drug - Concor Cor

Indications Concor

According to the instructions Concor is prescribed for hypertension arterial, chronic heart failure.

Positive reviews about Concor used in stable angina.

Contraindications

According to the instructions Concor is contraindicated in: acute heart failure, decompensated chronic heart failure (requiring treatment by means of a positive inotropic effect), cardiogenic shock, blockade sinoartrialnoy, AV-blockade of the 2nd and 3rd degree, sick sinus expressed by lowering the pressure, bradycardia, severe, heavy bronchial asthma, chronic obstructive pulmonary disease.

Use of Concor is also impossible when expressed pathologies of blood peripheral circulation, Raynaud's disease, pheochromocytoma, metabolic acidosis, hypersensitivity. You can not assign a means for children to 18L.

Precautions Concor tablets prescribed to patients with angina Printsmetalla, diabetes mellitus type 1, diabetes, with large fluctuations in blood glucose, hyperthyroidism, 1st degree AV blockade, severe renal insufficiency, hepatic function disorders, psoriasis, restrictive cardiomyopathy, congenital heart diseases and vice heart valve , chronic heart failure, a heart attack over the past three months, while a strict diet, desensitizing treatment.

Instructions for use Concor

 Concor 5 mg
 Concor take one p / day, usually in the morning with water. Grind and chew tablets Concor impossible.

When angina and arterial hypertension drug begin to take a dose of 5 mg a p / day. According to the testimony of the dose can be increased to 10 mg - also take one p / day. The maximum dose - 20 mg one p / day.

Before the treatment of chronic heart failure drug Concor Cor necessarily spend a special titration phase. Use tool only to patients diagnosed with stable chronic insufficiency without exacerbations.

Increasing the dose of Concor only under normal patient tolerance of the previous dose.

In the initial stages of treatment take 1, one 25mg p / day. After the dosage is gradually increased to 10, 7, 5, 5, 3, 75, 2, p is one 5mg / day. Each dose increase is carried out not less than two weeks. If an intolerance, reduce the dose. The permissible dose for the treatment Concor Cor chronic heart failure - one 10 mg p / day.

During titration, after it, the condition of patients with chronic heart failure can get worse, and may develop bradycardia, hypotension arterial. Once the patient is stabilized, titration is carried out again or continuing treatment.

Concor therapy with conventional long-term.

The permissible daily dose for patients with severe renal impairment and severe liver disease - 10 mg.

Elderly patients, patients with kidney disease and liver mild, moderate correction doses specified in the instructions Concor is required.

side effects

Use of Concor may lead to bradycardia, worsening congestive heart failure can cause a cold sensation and numbness in the limbs, lower pressure, orthostatic hypotension, conduction disturbances AV, headaches, loss of consciousness, dizziness, insomnia, nightmares, depression, hallucinations, hearing loss, conjunctivitis, lacrimation decrease.

There are reviews of Concor, cause bronchospasm in patients with bronchial asthma or obstructive airway diseases in the past.

Concor Cor also can cause diarrhea, constipation, hepatitis, nausea, vomiting, increased liver enzymes, muscle cramps and weakness, deterioration of potency, allergic skin reaction, alopecia, exacerbation of psoriasis, asthenia, fatigue.





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