Damage to the walls of the tiny blood vessels called microangiopathy. Microangiopathy can
It is a symptom of a variety of diseases.
Cerebral microangiopathy referred to damage of small vessels of the brain responsible for metabolism. This condition develops as a result of chronic cerebrovascular insufficiency. On the background of the human brain for a long time it suffers from a lack of oxygen and glucose - the main metabolic substrates that ensure the normal blood flow. Gradually developing brain dysfunction, which are the main target of the smallest brain arteries.
Microangiopathy of the brain leads to a diffuse bilateral ischemic lesions predominantly white matter, as well as numerous lacunar infarcts deep parts of the brain. Disruption of the normal functioning of the brain is clinically manifest in a variety of encephalopathies. Cerebral microangiopathy can develop as a result of atherosclerosis, or hypertension. Obviously, prevention of their occurrence is a timely and adequate treatment of the underlying disease.
Vascular lesions in diabetes, caused by high levels of blood glucose, and can manifest itself in the form of complications such as diabetic microangiopathy. In diabetic microangiopathy damaged arterioles, venules and capillaries of different localization.
Obviously, the clinical manifestations of diabetic microangiopathy can be very diverse. In any case, tissue metabolism difficult - the supply of nutrients and removal of decay products is reduced. As a consequence of growing tissue hypoxia - oxygen starvation. The vessels are narrowed, and the disease thus deteriorates.
Pressure increases vasoconstriction, high blood sugar causes inflammation and swelling of the vascular walls. The most acute diabetic microangiopathy occur in the kidneys and eyes, causing nephropathy and retinopathy of varying severity (particularly microaneurysms). Special attention of the clinician also require liver of diabetic microangiopathy.
Treatment of diabetic
microangiopathy is primarily in the normalization of blood sugar levels. Today, there are many modern drugs, allowing to achieve the desired effect. If necessary, patients prescribed insulin.
In addition, the hospital is appropriate reception angioprotectors - drugs that restore the walls of blood vessels and drugs that improve blood circulation (pentoxifylline, etc.). Also proved the effectiveness of antioxidants (vitamin E, selenium, etc.), vitamins B and lipoic acid preparations.
If necessary, requires normalization of blood pressure. Patients with diabetic microangiopathy recommended diet (sometimes low-salt) and the elimination of bad habits. It is advisable to conduct specific preventive examinations at least once a year.
Various microangiopathy can develop as a result of connective tissue disorders, infectious diseases, and the development of cancerous tumors. Microangiopathy may also manifest as renal failure and blood diseases (thrombotic microangiopathy). Microangiopathy are common symptoms of hypertension, occur as retinopathy AIDS.