Aspergillosis

 The initial form of pulmonary aspergillosis

Under aspergillosis refers to an infectious disease of the skin, lungs, sinuses, and other internal organs, caused by moldy fungi Aspergillus. In humans, these fungi by inhalation of spores fall. Of particular concern is the fact that they are widely distributed in nature and are found not only in the soil, flour or cereal, but just dust. There have been documented cases where certain forms of aspergillosis (eg, pulmonary aspergillosis) affects people, even in the hospital. Reason aspergillosis is still the same - not enough dust and responsible attitude to cleaning.

In some cases, the symptoms appear in the form of aspergillosis endogenous infection, but it is rather an exception to the rule is true only in relation to people with weakened immune systems. In recent years, is facing a problem of infection aspergillosis persons with immune deficiencies. Suffice it to say that the pulmonary aspergillosis detected in 20% of patients with HIV. First aspergillosis affects the lungs, pleura, and then the lymph nodes. As the blood vessels aspergillosis spreads to other organs. Very often, pulmonary aspergillosis transformed into generalized (septic), in 50% of cases leads to death of the patient. Note here that from human to human disease was not transmitted.

The symptoms of aspergillosis

The incubation period is not certain, but it is known that pulmonary aspergillosis may affect any tissue and organs. Doctors distinguish several forms of aspergillosis, depending on where it is localized pathogens.

Pulmonary aspergillosis - Aspergillus deposited on the surface layers of the mucous membranes in the lungs and bronchi. As the infection process involved more and more body systems. Patients are observed:

  • general weakness;
  • cough gray;
  • fever;
  • chills;
  • shortness of breath, chest pain;
  • lack of appetite;
  • bad dream.

Besides the above symptoms aspergillosis patients feel the taste of mold in your mouth. Sometimes found in the sputum greenish lumps, is a collection of fungi. Note also that the chronic form of aspergillosis is usually secondary. This means that in aspergillosis diagnosis of chronic treatment primarily involves searching the primary disease, the clinical symptoms of which often superimposed on secondary infection. The probability of death for this form of the disease varies from 20 to 37%.

Septic aspergillosis - the symptoms manifest themselves against sharp immunosuppression. Patients are observed: lesions of the gastrointestinal tract, mouth odor of mold, liquid foam chair, red nodules on the skin, brain abscesses. On the background of opportunistic infections and immunosuppression aspergillosis often leads to death of the patient (not less than 50% of cases).

Aspergillosis ENT - occurs after surgery on the inner ear or diseases of the larynx and the nasal mucosa. Aspergillosis is common among people who work in the textile mills and factories producing malt. Symptoms of this form of aspergillosis are similar to the symptoms of otitis media and external.

Treatment of aspergillosis

 Amphotericin B is the best medicine for the treatment of pulmonary aspergillosis
 Regardless of the type of infection, the treatment of aspergillosis is a very laborious task .  Chemotherapy and antibacterials do not lead to the desired effect, as well as all other known techniques to doctors fight infectious diseases .  For this reason, in recent years, aspergillosis diagnosis, treatment is based on the use of surgical techniques .  Patients underwent lobectomy with resection of the affected organs .  If the operation was carried out by a competent person in compliance with all established procedures - interference tolerated without complications and gives good predictions for the future .  With advanced forms of pulmonary aspergillosis surgical treatment used in conjunction with conservative methods .  Aspergillosis patients administered amphotericin B, oxacillin, nystatin, erythromycin, tetracycline antibiotics group .  At the same time people take vitamins .  It is also recommended that patients with aspergillosis restorative treatment .

When using the antifungal drug antibodies in the blood rises sharply, but the end of treatment it bounces back. If pulmonary aspergillosis leads to skin and mucous membranes, patients are recommended antimycotic and anti-inflammatory agents.

As for predictions of treatment. Pulmonary aspergillosis is fatal in 20-35% of cases (deaths in HIV-infected patients is 50%). When infection of the mucous membranes and upper respiratory organs prognosis is usually favorable. When septic form of aspergillosis - poor. It is important to timely detect disease symptoms and the correct diagnosis, so the sooner the patient see a doctor complaining of deterioration, the higher the chance that treatment will save the man's life.





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