Zinc - an important nutrient
element is always present in all cells of the body. The adult body contains an average of 1, 5-3 g of the substance. Zinc mainly accumulates in bone, skin, hair, semen. It is impossible to overstate the importance of this element for the proper functioning of the body, and excess zinc deficiency have a negative impact on human health. The daily requirement of zinc is an average of 8-25 mg per day. The danger of excess zinc as a metal, water and food for humans is low, since it does not accumulate. But long-term ingestion of high doses of this trace element can lead to an excess of zinc in the body and the development of a number of adverse effects. The threshold for toxicity of zinc is 600 mg / day (according to Prof. Rocky) and lethal dose - 6 g
The causes of excess zinc in the body
Even completely unbalanced diet can lead to a significant excess of zinc in the body
. Most excess of the normal concentration of the trace element in humans triggered by medication and dietary supplements that contain an excess of zinc in their composition
. So obvious signs of chronic excess zinc were detected in patients treated with 150 mg of trace elements in the day
. Sometimes it can be a danger and beverage packaging products, contribute to the formation of highly toxic zinc compounds (sulfates, chlorides and oxides)
. Thus recorded isolated cases of intoxication due to use of zinc in foods stored in galvanized or zinc containers completely
. Poisoning with zinc and its compounds in the production possible
. Oxide, chloride, and zinc sulfate used to produce glass in the manufacture of synthetic fibers, zinc paints, ceramics, matches, dental cement, pulp and paper, wood preservation, for tinning and soldering, etc.
. The excess of zinc in the solid state in the form of dust and relatively not dangerous
. Most threatening acute poisoning or chronic excess of zinc are its compounds
Symptoms excess zinc
Acute poisoning caused by taking just a large enough dose of trace elements. Thus the symptoms of excess zinc in an organism appear in a relatively short time. May experience nausea, vomiting, respiratory distress, erosion of the gastric mucosa, reduced function of the immune system. When zinc oxide poisoning through the respiratory tract occurs sweetish taste in the mouth, then thirst, choking, dry cough, oppressive chest pain, drowsiness, chills. By ingestion of excess zinc in the form of metal salts occurs
taste, burn the mucous of the digestive tract, nausea, vomiting, diarrhea, abdominal pain, cramps in the calf muscles, drop in blood pressure. Symptomatic excess zinc may become fibrotic degeneration of pancreas. Often there is excess of the normal numbers of blood glucose.
Chronic toxicity of zinc can lead to deterioration of the nail, skin, hair loss, weakening function prostate, pancreas, liver, development of various autoimmune diseases. In chronic excess of zinc decreases absorption of copper, manganese, iron from food and their secondary deficiency occurs. One symptom of excess zinc in the body may be a slowing of bone growth by reducing their mineralization. The weakening of the tendon reflexes and progressive weakness may be symptoms of excess zinc in the blood. There is evidence of a carcinogenic effect of zinc and its compounds.
Treatment of conditions associated with an excess of zinc in the body
In acute and chronic excess of zinc in the body need medical help. Treatment largely directed at eliminating the symptoms of excess zinc. In acute poisoning arisen therapy is stationary. As an antidote used unitiol. Concerning chronic forms of excess zinc in the body to date decisive role to the prevention.