Huntington's Disease

Chorea, Huntington's disease, or in practice quite rare. In European populations the prevalence of the disease varies from 3 to 7 people per 100 000, while the other races - 1 per 100 000.  Huntington's disease - an inherited abnormality of the brain

This hereditary pathology of the brain first appears erratic involuntary movements and facial expressions, increasing anxiety, the destruction of the mental health of the individual and ends with dementia, that is dementia.

Diagnosis of Huntington's disease

If you suspect a disease, Huntington analyzes clinical and collecting family history of the patient. The vast majority of brain scans allow one to confirm or deny the preliminary diagnosis. If there remain some doubts, it is advisable to conduct genetic testing. This type of study is very effective in adults, whereas in children are mainly used other methods of diagnosis.

Symptoms of Huntington's disease

It is noted that most of the symptoms of Huntington's disease appear for the first time at the age of about 30 years, though documented cases as the earlier and much later start. Initially, they are treated as the actual impulsive and uncontrolled movement, and on the contrary - a decrease motor activity and difficulty in movement. Then there are problems with speech, disturbed coordination of movements.

With the further development of the disease all muscle function gradually decreases. Self chewing and swallowing require much effort. Another common symptom of Huntington's disease in the middle stage is uncontrolled grimacing, joined by a sleep disorder that develops as a result of frequent and chaotic movements of the eyeballs.

All of these functions adversely affect the mental faculties of man, though in each case the extent of this influence is especially individual. The first to suffer abstract thinking, a person's ability to evaluate their actions adequately behave in society, to plan their own activities. Then pointed out the problems with memory, emotional and self-centered greed, obsession and depression, panic, and even aggressive manifestations.

Patients with Huntington's disease gradually cease to recognize loved ones, they hypertrophy addictions (alcoholism, love to gamble), and sexual needs.

The last stage of Huntington's disease is characterized by the fact that the patient loses the ability to move independently. Death occurs from cardiovascular disease, pneumonia, etc.  Reduced motor activity - one of the first symptoms of Huntington's disease

Causes

In 1993, it was well established that Huntington's disease develops as a result of congenital genetic pathology. Protein huntingtin (whose function is today not fully inserted) is normally present in the body of a healthy person in a specific amount. In humans, the same number of Huntington's disease this protein higher than normal.

Modern research shows that the likelihood of developing Huntington's disease in children born to parents of patients is 50%.

Treatment of Huntington's disease

Specific treatment of Huntington's disease, modern medicine is unable to offer, although the clinical testing different techniques are held regularly. The therapy in these patients is reduced to the use of symptomatic drugs.





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